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Context Info
Confidence 0.18
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.74
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (KIT) extracellular space (KIT) plasma membrane (KIT)
nucleus (KIT) cytoplasm (KIT)
Anatomy Link Frequency
early erythroblasts 3
MIR221 (Homo sapiens)
KIT (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thyroid Neoplasm 3 86.16 High High
Pancreatic Cancer 7 84.76 Quite High
Chronic Lymphoid Leukemia 8 77.88 Quite High
Malignant Neoplastic Disease 5 66.16 Quite High
Targeted Disruption 1 61.24 Quite High
Pleomorphic Adenoma 1 58.40 Quite High
Cancer 50 57.36 Quite High
Head & Neck Cancer 1 50.56 Quite High
Apoptosis 12 42.96 Quite Low
Glioblastoma 3 31.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The decline of miR-221 and miR-222 during exponential erythropoietic growth unblocked Kit protein production at mRNA level, thus leading to expansion of early erythroblasts [26].
Negative_regulation (decline) of miR-221 in early erythroblasts Negative_regulation (unblocked) of Gene_expression (production) of Kit in early erythroblasts
1) Confidence 0.18 Published 2007 Journal Mol Cancer Section Body Doc Link PMC2098778 Disease Relevance 0.74 Pain Relevance 0

General Comments

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