INT217144

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Context Info
Confidence 0.06
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.03
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (TPM1) cytosol (TPM1) cytoskeleton (TPM1)
cytoskeleton organization (TPM1) cytoplasm (TPM1)
MIR21 (Homo sapiens)
TPM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 1 45.04 Quite Low
Chronic pancreatitis 2 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 4 100.00 Very High Very High Very High
Cancer 50 97.80 Very High Very High Very High
Malignant Neoplastic Disease 5 83.60 Quite High
Apoptosis 12 83.52 Quite High
Head & Neck Cancer 1 59.12 Quite High
Lung Cancer 13 47.36 Quite Low
Pleomorphic Adenoma 1 44.08 Quite Low
Targeted Disruption 1 37.68 Quite Low
Chronic Lymphoid Leukemia 8 5.00 Very Low Very Low Very Low
Pancreatic Cancer 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Downregulation of tropomyosin 1 in breast cancer by miR-21 might explain why suppression of miR-21 could inhibit tumor growth, further supporting the notion that miR-21 functions as an oncogene [20].
miR-21 Negative_regulation (Downregulation) of tropomyosin 1 associated with cancer and breast cancer
1) Confidence 0.06 Published 2007 Journal Mol Cancer Section Body Doc Link PMC2098778 Disease Relevance 1.03 Pain Relevance 0

General Comments

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