INT217179

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.90
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (AXL) signal transduction (AXL) plasma membrane (AXL)
AXL (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Somatostatin 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Serotonin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 4 100.00 Very High Very High Very High
Thyroid Neoplasm 91 99.36 Very High Very High Very High
Cancer 84 95.24 Very High Very High Very High
Genetic Translocation 3 94.04 High High
Adenocarcinoma 3 86.64 High High
Lung Cancer 14 78.88 Quite High
Neurofibromatosis 2 1 77.28 Quite High
Carcinoma 3 73.84 Quite High
Malignant Neoplastic Disease 6 69.36 Quite High
Colon Cancer 6 63.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
They found that the loss of miRNA-directed repression of an oncogene provided a mechanism for tumorigenesis, and disrupting a single miRNA-target interaction could produce an observable phenotype in mammalian cells [43].
Negative_regulation (repression) of oncogene associated with repression
1) Confidence 0.01 Published 2007 Journal Mol Cancer Section Body Doc Link PMC2098778 Disease Relevance 1.11 Pain Relevance 0
Inhibitors of the activated RET proto-oncogene and other RTK inhibitors appear particularly promising, based on the high prevalence of mutated oncogenes and specific expression patterns in MTC [2].
Negative_regulation (Inhibitors) of oncogene associated with thyroid neoplasm
2) Confidence 0.00 Published 2009 Journal Journal of Oncology Section Body Doc Link PMC2798103 Disease Relevance 0.79 Pain Relevance 0

General Comments

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