INT217193

Context Info Confidence 0.01 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.12 Pain Relevance 0

cell differentiation (AXL) signal transduction (AXL) plasma membrane (AXL)

AXL (Homo sapiens)

Pain Link Frequency Relevance Heat Chronic pancreatitis 2 5.00 addiction 1 5.00 Kinase C 1 5.00

Disease Link Frequency Relevance Heat Repression 4 100.00 Cancer 50 96.16 Genetic Translocation 3 94.96 Adenocarcinoma 3 87.56 Lung Cancer 13 78.88 Neurofibromatosis 2 1 78.20 Malignant Neoplastic Disease 5 70.28 Colon Cancer 6 63.92 Skin Cancer 1 57.04 Hypoxia 1 33.84

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

They found that the loss of miRNA-directed repression of an oncogene provided a mechanism for tumorigenesis, and disrupting a single miRNA-target interaction could produce an observable phenotype in mammalian cells [43].

Negative_regulation (loss) of Negative_regulation (repression) of oncogene associated with repression

1) Confidence 0.01 Published 2007 Journal Mol Cancer Section Body Doc Link PMC2098778 Disease Relevance 1.12 Pain Relevance 0

General Comments

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