INT217225

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Context Info
Confidence 0.55
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.40
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear chromosome (HMGA2) protein binding transcription factor activity (HMGA2) DNA binding (HMGA2)
mitosis (HMGA2) nucleus (HMGA2) nucleic acid binding transcription factor activity (HMGA2)
HMGA2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 4 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 8 100.00 Very High Very High Very High
Cancer 100 99.98 Very High Very High Very High
Genetic Translocation 6 99.38 Very High Very High Very High
Adenocarcinoma 6 91.36 High High
Neurofibromatosis 2 2 82.00 Quite High
Malignant Neoplastic Disease 10 74.08 Quite High
Lung Cancer 26 72.00 Quite High
Colon Cancer 12 67.72 Quite High
Skin Cancer 2 50.16 Quite High
Hypoxia 2 26.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mayr et al. reported that the chromosomal translocations associating with human tumors disrupted the repression of High mobility group A2 (Hmga2) by let-7 miRNA.
Negative_regulation (disrupted) of Negative_regulation (repression) of High mobility group A2 associated with cancer, genetic translocation and repression
1) Confidence 0.55 Published 2007 Journal Mol Cancer Section Body Doc Link PMC2098778 Disease Relevance 1.17 Pain Relevance 0
Mayr et al. reported that the chromosomal translocations associating with human tumors disrupted the repression of High mobility group A2 (Hmga2) by let-7 miRNA.
Negative_regulation (disrupted) of Negative_regulation (repression) of Hmga2 associated with cancer, genetic translocation and repression
2) Confidence 0.40 Published 2007 Journal Mol Cancer Section Body Doc Link PMC2098778 Disease Relevance 1.22 Pain Relevance 0

General Comments

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