INT217277

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Cpox, Ptges) mitochondrion (Cpox) oxidoreductase activity (Cpox)
nucleus (Ptges)
Anatomy Link Frequency
microglia 2
Cpox (Rattus norvegicus)
Ptges (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 1 88.08 High High
COX-2 inhibitor 2 24.72 Low Low
ischemia 7 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Stimulus evoked pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 7 88.08 High High
Brain Injury 12 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Cv General 4 Under Development 3 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 3 5.00 Very Low Very Low Very Low
Brain Hemorrhage 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Parkinson's Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RT-PCR analysis reveals that COX-1 inhibition by SC-560 or VAS failed to reduce mPGES-1 expression in LPS-activated primary microglia (Fig. 7A and 7B).
COX Neg (failed) Negative_regulation (reduce) of Gene_expression (expression) of mPGES-1 in microglia
1) Confidence 0.01 Published 2007 Journal J Neuroinflammation Section Body Doc Link PMC2100038 Disease Relevance 0.09 Pain Relevance 0.04

General Comments

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