INT217341

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.25
First Reported 2007
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 4.97
Pain Relevance 1.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CXCL10) extracellular space (CXCL10) extracellular region (CXCL10)
cell-cell signaling (CXCL10)
Anatomy Link Frequency
lung 2
CXCL10 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 64 100.00 Very High Very High Very High
Inflammation 87 87.64 High High
cytokine 70 81.28 Quite High
Inflammatory response 10 72.28 Quite High
imagery 120 50.00 Quite Low
metalloproteinase 10 37.28 Quite Low
cva 28 17.44 Low Low
rheumatoid arthritis 12 5.00 Very Low Very Low Very Low
headache 5 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Influenza Virus Infection 18 99.02 Very High Very High Very High
Infection 207 98.12 Very High Very High Very High
Weight Loss 2 97.96 Very High Very High Very High
Atherosclerosis 204 94.72 High High
Atherosclerotic Plaque 38 94.24 High High
Cardiovascular Disease 38 88.72 High High
INFLAMMATION 93 87.64 High High
Critical Illness 37 87.36 High High
Dengue 240 85.76 High High
Disease 61 81.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the ferret model with 27% mortality based on the >20% weight loss following infection with A/California/07/2009 pandemic influenza virus [22], sequential lung sampling documented decreased gene expression of CCL2, CXCL10, TNFA and IL1B on day 7 when animals show highest weight loss.
Negative_regulation (decreased) of Gene_expression (expression) of CXCL10 in lung associated with weight loss, influenza virus infection and infection
1) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2948498 Disease Relevance 1.04 Pain Relevance 0.21
Interestingly, the Th2-adjuvant alum considerably inhibits TLR-induced production of CXCL10 [77].
Negative_regulation (inhibits) of Gene_expression (production) of CXCL10
2) Confidence 0.20 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2660151 Disease Relevance 0.19 Pain Relevance 0.11
B could all induce the production of IP-10 and I-TAC, prevention of IP-10 and I-TAC via NF-?
Negative_regulation (prevention) of Gene_expression (production) of IP-10
3) Confidence 0.12 Published 2007 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2100376 Disease Relevance 1.23 Pain Relevance 0.12
The addition of anti-IP-10 neutralizing antibody blocked the production of endogenous IP-10 and significantly enhanced the replication of DEN-2 (Fig. 4A).
Negative_regulation (blocked) of Gene_expression (production) of IP-10
4) Confidence 0.12 Published 2011 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC3014977 Disease Relevance 0.35 Pain Relevance 0.03
We used an anti-IP-10 neutralizing mAb to block endogenous IP-10 production by MDDCs.
Negative_regulation (block) of Gene_expression (production) of IP-10
5) Confidence 0.09 Published 2011 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC3014977 Disease Relevance 0.44 Pain Relevance 0
CSF-1 induced expression of the proatherogenic chemokines CXCL10/IP-10, CCL2 and CCL7 but repressed expression of the antiatherogenic chemokine receptor CXCR4 [53].
Negative_regulation (chemokines) of Gene_expression (expression) of IP-10 associated with chemokine
6) Confidence 0.05 Published 2010 Journal Eur J Nucl Med Mol Imaging Section Body Doc Link PMC2975909 Disease Relevance 0.83 Pain Relevance 0.27
CSF-1 induced expression of the proatherogenic chemokines CXCL10/IP-10, CCL2 and CCL7 but repressed expression of the antiatherogenic chemokine receptor CXCR4 [53].
Negative_regulation (repressed) of Gene_expression (expression) of IP-10 associated with chemokine
7) Confidence 0.05 Published 2010 Journal Eur J Nucl Med Mol Imaging Section Body Doc Link PMC2975909 Disease Relevance 0.89 Pain Relevance 0.30

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox