INT217378

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Context Info
Confidence 0.30
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

T(12;16)1Cje (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 18 54.20 Quite High
Serotonin 1 19.84 Low Low
Inflammation 20 5.00 Very Low Very Low Very Low
long-term potentiation 8 5.00 Very Low Very Low Very Low
Thalamus 8 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
medulla 3 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Limbic system 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 171 99.68 Very High Very High Very High
Alzheimer's Dementia 160 91.56 High High
Generaliased Trisomy 3 35.32 Quite Low
Down Syndrome 8 28.12 Quite Low
Vascular Disease 16 25.80 Quite Low
Amyloid Plaque 38 5.00 Very Low Very Low Very Low
Cognitive Disorder 27 5.00 Very Low Very Low Very Low
INFLAMMATION 21 5.00 Very Low Very Low Very Low
Disease 16 5.00 Very Low Very Low Very Low
Death 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There is no enlargement of the endosomes in the Ts1Cje mice (no APP overexpression) or in transgenic mice overexpressing APP751 with the Swedish double mutation alone or in combination with the London mutation [49].
Neg (no) Gene_expression (overexpression) of Ts1Cje associated with targeted disruption
1) Confidence 0.30 Published 2007 Journal Acta Neuropathol Section Body Doc Link PMC2100431 Disease Relevance 0.27 Pain Relevance 0.03

General Comments

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