INT217400

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Context Info
Confidence 0.17
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.43
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Psen1, Bace1) endoplasmic reticulum (Psen1, Bace1) peptidase activity (Psen1, Bace1)
endosome (Bace1) mitochondrion (Psen1) intracellular (Psen1)
Psen1 (Mus musculus)
Bace1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 40 5.00 Very Low Very Low Very Low
Hippocampus 36 5.00 Very Low Very Low Very Low
long-term potentiation 16 5.00 Very Low Very Low Very Low
Thalamus 16 5.00 Very Low Very Low Very Low
Spinal cord 8 5.00 Very Low Very Low Very Low
medulla 6 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Limbic system 6 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
cerebral cortex 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 320 85.64 High High
Vascular Disease 32 82.40 Quite High
Amyloid Plaque 76 80.44 Quite High
Disease 32 33.52 Quite Low
Neurodegenerative Disease 18 7.52 Low Low
Targeted Disruption 342 5.00 Very Low Very Low Very Low
Cognitive Disorder 54 5.00 Very Low Very Low Very Low
INFLAMMATION 42 5.00 Very Low Very Low Very Low
Death 30 5.00 Very Low Very Low Very Low
Frailty 22 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-secretase complex (made of presenilin1 (PS1) or presenilin 2 (PS2), Pen 2, nicastrin and APH 1)—for a review see [340].
presenilin1 Binding (complex) of secretase
1) Confidence 0.17 Published 2007 Journal Acta Neuropathol Section Body Doc Link PMC2100431 Disease Relevance 0.71 Pain Relevance 0
-secretase complex (made of presenilin1 (PS1) or presenilin 2 (PS2), Pen 2, nicastrin and APH 1)—for a review see [340].
PS1 Binding (complex) of secretase
2) Confidence 0.17 Published 2007 Journal Acta Neuropathol Section Body Doc Link PMC2100431 Disease Relevance 0.72 Pain Relevance 0

General Comments

This test has worked.

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