INT217429

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Context Info
Confidence 0.38
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 22
Total Number 23
Disease Relevance 42.17
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (SLC9A6) transport (SLC9A6) mitochondrion (SLC9A6)
plasma membrane (SLC9A6) transmembrane transport (SLC9A6)
Anatomy Link Frequency
skin 3
reservoirs 2
blood 1
SLC9A6 (Homo sapiens)
Pain Link Frequency Relevance Heat
backache 10 99.38 Very High Very High Very High
topical agent 51 97.40 Very High Very High Very High
imagery 5 94.80 High High
Inflammatory marker 5 85.28 High High
Angina 1 77.92 Quite High
referred pain 1 64.48 Quite High
tolerance 6 54.40 Quite High
Pain 19 51.12 Quite High
Arthritis 6 50.00 Quite Low
adenocard 4 32.96 Quite Low
Disease Link Frequency Relevance Heat
Mrsa Infection 2596 100.00 Very High Very High Very High
Infection 839 100.00 Very High Very High Very High
Wound Infection 119 100.00 Very High Very High Very High
Mediastinitis 3 99.96 Very High Very High Very High
Injury 1124 99.60 Very High Very High Very High
Bacteremia 292 99.60 Very High Very High Very High
Low Back Pain 10 99.38 Very High Very High Very High
Pressure Volume 2 Under Development 2 99.10 Very High Very High Very High
Fever 10 98.84 Very High Very High Very High
Nosocomial And Community Acquired Bacterial Infections 136 98.72 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, if there is a high regional incidence of CA-MRSA or risk factors for this infection are increased, appropriate CA-MRSA antibiotics should be selected (Table 6).
Positive_regulation (increased) of MRSA associated with mrsa infection and infection
1) Confidence 0.38 Published 2007 Journal Journal of Burns and Wounds Section Body Doc Link PMC2104747 Disease Relevance 1.46 Pain Relevance 0
The multiantibiotic resistant HA-MRSA, typically transmitted by hand-to-skin contact, is an increasing cause of bacteremia worldwide.
Positive_regulation (increasing) of HA-MRSA in skin associated with mrsa infection and bacteremia
2) Confidence 0.27 Published 2007 Journal Journal of Burns and Wounds Section Body Doc Link PMC2104747 Disease Relevance 2.13 Pain Relevance 0
Objective: Our objective is to define this current epidemic problem caused by both community-acquired MRSA (CA-MRSA) and hospital-acquired MRSA (HA-MRSA), focusing on the similarities and differences between these 2 isolates as well as the impact on wound management decisions.
Positive_regulation (acquired) of MRSA associated with mrsa infection and injury
3) Confidence 0.27 Published 2007 Journal Journal of Burns and Wounds Section Abstract Doc Link PMC2104747 Disease Relevance 1.40 Pain Relevance 0
To date, bacteremias continue to be a much more common nosocomial infection problem with HA-MRSA.2,11,12 Recently, there has been a marked increase in the prevalence of MRSA throughout the world, especially in the past decade.13–18 The MRSA infections are tracked through causes of a bacteremia,13–19 most of which could be considered HA-MRSA due to the presence of risk factors.
Positive_regulation (increase) of MRSA associated with mrsa infection, bacteremia, nosocomial and community acquired bacterial infections and infection
4) Confidence 0.27 Published 2007 Journal Journal of Burns and Wounds Section Body Doc Link PMC2104747 Disease Relevance 2.70 Pain Relevance 0
As of 2001, the Centers for Disease Control and Prevention (CDC) estimated that there were an estimated 2 million MRSA carriers in the United States alone.2830 This number has certainly increased since that time.
Positive_regulation (increased) of MRSA associated with mrsa infection and disease
5) Confidence 0.27 Published 2007 Journal Journal of Burns and Wounds Section Body Doc Link PMC2104747 Disease Relevance 1.48 Pain Relevance 0
Community acquired MRSA is quite antibiotic sensitive.
Positive_regulation (acquired) of MRSA associated with mrsa infection
6) Confidence 0.27 Published 2007 Journal Journal of Burns and Wounds Section Body Doc Link PMC2104747 Disease Relevance 1.46 Pain Relevance 0
Objective: Our objective is to define this current epidemic problem caused by both community-acquired MRSA (CA-MRSA) and hospital-acquired MRSA (HA-MRSA), focusing on the similarities and differences between these 2 isolates as well as the impact on wound management decisions.
Positive_regulation (acquired) of HA-MRSA associated with mrsa infection and injury
7) Confidence 0.27 Published 2007 Journal Journal of Burns and Wounds Section Abstract Doc Link PMC2104747 Disease Relevance 1.45 Pain Relevance 0
Rao and colleagues14 screened all patients admitted through a hospital Emergency Department for MRSA carriage and demonstrated that 15.5% of the patients found to be positive for MRSA did not have recognized risk factors such as recent hospital admission, advanced age or care home residency.
Positive_regulation (positive) of MRSA associated with mrsa infection and emergencies
8) Confidence 0.27 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2964962 Disease Relevance 1.34 Pain Relevance 0
In late 2006 the UK Department of Health recommended that all elective admissions in England should be screened for MRSA and if found positive should then undergo decolonization regime.5 Following comments by the Royal College of Ophthalmologists and others, it was clarified in refreshed operational guidance to the National Health Service (NHS) in early 2008 that day-case ophthalmology patients in the English NHS did not have to undergo routine MRSA screening.6,7 A survey of UK ophthalmology departments undertaken in September 2005 demonstrated significant variability surrounding local MRSA screening practices.4 Following a consideration of available evidence The MRSA Screening Pathfinder Programme in Scotland has not recommended universal MRSA screening requirements in its Interim Report.8 MRSA screening is not currently required in England or Scotland for day-care ophthalmology patients, but is required for admitted ophthalmic patients.7,9
Positive_regulation (requirements) of MRSA associated with mrsa infection
9) Confidence 0.27 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2964962 Disease Relevance 1.27 Pain Relevance 0
There is now a well-recognized increase in MRSA colonization and infection in chronic wounds.52–57 The increase appears to be comparable to the worldwide increase in MRSA in acute wounds.
Positive_regulation (increase) of MRSA associated with mrsa infection, injury and infection
10) Confidence 0.25 Published 2007 Journal Journal of Burns and Wounds Section Body Doc Link PMC2104747 Disease Relevance 3.13 Pain Relevance 0.04
It appears that MRSA colonization and infection are clearly increasing in the chronic wound population.
Positive_regulation (increasing) of MRSA associated with mrsa infection, injury and infection
11) Confidence 0.25 Published 2007 Journal Journal of Burns and Wounds Section Body Doc Link PMC2104747 Disease Relevance 1.93 Pain Relevance 0.09
Conclusion: Conclusions include the fact that both HA-MRSA and CA-MRSA wound infections are rapidly increasing, especially with CA-MRSA.
Positive_regulation (increasing) of MRSA associated with mrsa infection and wound infection
12) Confidence 0.25 Published 2007 Journal Journal of Burns and Wounds Section Abstract Doc Link PMC2104747 Disease Relevance 2.16 Pain Relevance 0
Conclusion: Conclusions include the fact that both HA-MRSA and CA-MRSA wound infections are rapidly increasing, especially with CA-MRSA.
Positive_regulation (increasing) of HA-MRSA associated with mrsa infection and wound infection
13) Confidence 0.25 Published 2007 Journal Journal of Burns and Wounds Section Abstract Doc Link PMC2104747 Disease Relevance 2.30 Pain Relevance 0
Because of the rapid increase in CA-MRSA acute infections, the CDC recently published new Guidelines for the Management of Acute Skin and Soft Tissue
Positive_regulation (increase) of MRSA in Skin associated with mrsa infection and infection
14) Confidence 0.25 Published 2007 Journal Journal of Burns and Wounds Section Body Doc Link PMC2104747 Disease Relevance 1.64 Pain Relevance 0.05
Also, MRSA is now the most identifiable cause of acute skin and soft-tissue infections seen in the urban emergency department setting.3–6
Positive_regulation (cause) of MRSA in skin associated with mrsa infection, emergencies and infection
15) Confidence 0.25 Published 2007 Journal Journal of Burns and Wounds Section Body Doc Link PMC2104747 Disease Relevance 1.31 Pain Relevance 0
There is now a well-recognized increase in MRSA colonization and infection in chronic wounds.52–57 The increase appears to be comparable to the worldwide increase in MRSA in acute wounds.
Positive_regulation (increase) of MRSA associated with mrsa infection, injury and infection
16) Confidence 0.25 Published 2007 Journal Journal of Burns and Wounds Section Body Doc Link PMC2104747 Disease Relevance 2.98 Pain Relevance 0.04
There are large and increasing reservoirs of CA-MRSA and HA-MRSA worldwide leading to more bacteremias and wound problems.
Positive_regulation (increasing) of HA-MRSA in reservoirs associated with mrsa infection, bacteremia and injury
17) Confidence 0.25 Published 2007 Journal Journal of Burns and Wounds Section Abstract Doc Link PMC2104747 Disease Relevance 2.53 Pain Relevance 0
Conclusion: Conclusions include the fact that both HA-MRSA and CA-MRSA wound infections are rapidly increasing, especially with CA-MRSA.
Positive_regulation (increasing) of MRSA associated with mrsa infection and wound infection
18) Confidence 0.25 Published 2007 Journal Journal of Burns and Wounds Section Abstract Doc Link PMC2104747 Disease Relevance 2.28 Pain Relevance 0
There are large and increasing reservoirs of CA-MRSA and HA-MRSA worldwide leading to more bacteremias and wound problems.
Positive_regulation (increasing) of MRSA in reservoirs associated with mrsa infection, bacteremia and injury
19) Confidence 0.11 Published 2007 Journal Journal of Burns and Wounds Section Abstract Doc Link PMC2104747 Disease Relevance 2.52 Pain Relevance 0
In a recent animal study, linezolid was shown to be effective against experimentally induced MRSA mediastinitis, with no additional benefit from the addition of rifampicin [12].
Positive_regulation (induced) of MRSA associated with mrsa infection and mediastinitis
20) Confidence 0.08 Published 2008 Journal J Med Case Reports Section Body Doc Link PMC2390578 Disease Relevance 1.20 Pain Relevance 0.14

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