INT217477

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Context Info
Confidence 0.32
First Reported 2007
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Traf6, Nup62) nucleus (Traf6, Nup62) transport (Nup62)
nuclear envelope (Nup62) protein complex assembly (Traf6) protein complex (Traf6)
Traf6 (Mus musculus)
Nup62 (Mus musculus)
Pain Link Frequency Relevance Heat
Nerve growth factor 4 92.00 High High
cytokine 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bone Disease 51 90.64 High High
Disease 15 77.68 Quite High
Injury 1 76.04 Quite High
Syndrome 9 5.00 Very Low Very Low Very Low
Hypercalcemia 4 5.00 Very Low Very Low Very Low
Osteoporosis 4 5.00 Very Low Very Low Very Low
Osteogenic Sarcomas 3 5.00 Very Low Very Low Very Low
Osteolysis 2 5.00 Very Low Very Low Very Low
Frontotemporal Dementia 2 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Whether p62 performs a similar role in RANK signalling awaits confirmation, although interestingly, p62-mediated ubiquitylation of TRAF6 in response to NFG appears to require the ubiquitin binding activity of p62 [34].
TRAF6 Spec (appears) Positive_regulation (require) of p62 Binding (activity) of
1) Confidence 0.32 Published 2007 Journal BMC Biochem Section Body Doc Link PMC2106369 Disease Relevance 0.47 Pain Relevance 0.09

General Comments

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