INT217486

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Context Info
Confidence 0.03
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.19
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Sqstm1) endosome (Sqstm1) nucleus (Sqstm1)
cytoplasm (Sqstm1)
Anatomy Link Frequency
body 1
PDB1 (Homo sapiens)
Sqstm1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 1 84.56 Quite High
rheumatoid arthritis 2 77.12 Quite High
Nerve growth factor 4 46.72 Quite Low
cytokine 3 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bone Disease 51 100.00 Very High Very High Very High
Frontotemporal Dementia 2 100.00 Very High Very High Very High
Muscle Disease 2 99.98 Very High Very High Very High
Osteolysis 2 98.46 Very High Very High Very High
INFLAMMATION 1 84.56 Quite High
Rheumatoid Arthritis 2 77.12 Quite High
Disease 15 76.12 Quite High
Osteoporosis 4 75.32 Quite High
Hypercalcemia 4 73.24 Quite High
Syndrome 9 70.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PDB, Paget's disease of bone; FEO, familial expansile osteolysis; ESH, expansile skeletal hyperphosphatasia; IBMPFD, inclusion body myopathy associated with PDB and frontotemporal dementia; SQSTM1, Sequestosome 1; RANK, receptor activator of NF-?
PDB Binding (associated) of Sequestosome 1 in body associated with frontotemporal dementia, muscle disease, osteolysis and bone disease
1) Confidence 0.03 Published 2007 Journal BMC Biochem Section Body Doc Link PMC2106369 Disease Relevance 1.19 Pain Relevance 0.08

General Comments

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