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Context Info
Confidence 0.24
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.96
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ocln) structural molecule activity (Ocln) plasma membrane (Ocln)
Ocln (Mus musculus)
Pain Link Frequency Relevance Heat
Crohn's disease 8 90.92 High High
Inflammation 20 55.68 Quite High
cytokine 4 54.12 Quite High
Versed 4 5.00 Very Low Very Low Very Low
tetrodotoxin 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colitis 62 97.66 Very High Very High Very High
Disease 8 90.92 High High
Weight Loss 4 89.28 High High
Gastrointestinal Disease 8 75.32 Quite High
Inflammatory Bowel Disease 34 66.36 Quite High
INFLAMMATION 18 55.68 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 10 19.88 Low Low
Injury 2 18.16 Low Low
Infection 8 17.88 Low Low
Diarrhoea 14 16.04 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, using a mouse colitis model, Resta-Lenert et al. have shown that the increase in intestinal permeability is associated with a decrease of occludin and ZO-1 phosphorylation [54].
Phosphorylation (phosphorylation) of occludin associated with colitis
1) Confidence 0.24 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2110898 Disease Relevance 0.77 Pain Relevance 0.07
This hypothesis is also supported by a recent study demonstrating that probiotic Streptococcus thermophilus and Lactobacillus acidophilus can prevent invasion of enteroinvasive E. coli and enhance intestinal epithelial barrier function by amplifying phosphorylation of occludin and ZO-1 in vitro [19].
Phosphorylation (phosphorylation) of occludin
2) Confidence 0.18 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2110898 Disease Relevance 0.19 Pain Relevance 0.05

General Comments

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