INT217502

Context Info Confidence 0.13 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.19 Pain Relevance 0.06

cytosol (Ocln) structural molecule activity (Ocln) plasma membrane (Ocln)

Ocln (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 10 56.12 cytokine 2 54.56 Crohn's disease 4 8.52 Versed 2 5.00 tetrodotoxin 1 5.00 anesthesia 1 5.00

Disease Link Frequency Relevance Heat Gastrointestinal Disease 4 75.76 Inflammatory Bowel Disease 17 56.84 INFLAMMATION 9 56.12 Acquired Immune Deficiency Syndrome Or Hiv Infection 5 20.32 Infection 4 18.32 Diarrhoea 7 16.48 Disease 4 8.52 Colitis 31 5.00 Body Weight 7 5.00 Weight Loss 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

This hypothesis is also supported by a recent study demonstrating that probiotic Streptococcus thermophilus and Lactobacillus acidophilus can prevent invasion of enteroinvasive E. coli and enhance intestinal epithelial barrier function by amplifying phosphorylation of occludin and ZO-1 in vitro [19].

Positive_regulation (amplifying) of Phosphorylation (phosphorylation) of occludin

1) Confidence 0.13 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2110898 Disease Relevance 0.19 Pain Relevance 0.06

General Comments

This test has worked.