INT217509

Context Info Confidence 0.35 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.12 Pain Relevance 0

Golgi apparatus (Tjp1) plasma membrane (Tjp1) nucleus (Tjp1) cytoplasm (Tjp1)

Tjp1 (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 10 5.00 Crohn's disease 4 5.00 cytokine 2 5.00 Versed 2 5.00 tetrodotoxin 1 5.00 anesthesia 1 5.00

Disease Link Frequency Relevance Heat Colitis 31 64.32 Inflammatory Bowel Disease 17 59.20 INFLAMMATION 9 5.00 Diarrhoea 7 5.00 Body Weight 7 5.00 Acquired Immune Deficiency Syndrome Or Hiv Infection 5 5.00 Gastrointestinal Disease 4 5.00 Disease 4 5.00 Infection 4 5.00 Weight Loss 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Due to the important functional role of ZO-1 in the junctional complex, these findings suggest that enhancement of the intestinal epithelial barrier function by EcN could at least in part be attributed to up-regulation of ZO-1.

Positive_regulation (attributed) of Regulation (regulation) of ZO-1

1) Confidence 0.35 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2110898 Disease Relevance 0.12 Pain Relevance 0

General Comments

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