INT217569

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Context Info
Confidence 0.36
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 1.07
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Wnt1) extracellular space (Wnt1) extracellular region (Wnt1)
proteinaceous extracellular matrix (Wnt1) plasma membrane (Wnt1) cell-cell signaling (Wnt1)
Anatomy Link Frequency
embryos 2
cranial neural crest 1
Wnt1 (Mus musculus)
Pain Link Frequency Relevance Heat
gABA 1 83.20 Quite High
Glutamate 14 82.96 Quite High
Neurotransmitter 1 32.80 Quite Low
midbrain 6 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
vagus nerve 3 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Somatostatin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 57 95.52 Very High Very High Very High
Targeted Disruption 81 83.12 Quite High
Persistent Truncus Arteriosus 12 81.80 Quite High
Adhesions 17 76.56 Quite High
Congenital Anomalies 21 58.84 Quite High
Cleft Palate 24 5.00 Very Low Very Low Very Low
Ventricular Heart Septal Defects 12 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Syndrome 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The Frizzled receptors bind among others the Wnt ligand and play an important role in embryonic development.
Wnt Binding (bind) of
1) Confidence 0.36 Published 2007 Journal BMC Genomics Section Body Doc Link PMC2117022 Disease Relevance 0.13 Pain Relevance 0.15
In addition, the branchial arches of Spry1;R26R:Wnt1-Cre embryos were smaller than that of the R26R;Wnt1-Cre control embryos, however ?
Wnt1 Binding (embryos) of in embryos
2) Confidence 0.32 Published 2010 Journal BMC Dev Biol Section Body Doc Link PMC2874773 Disease Relevance 0.21 Pain Relevance 0
Although our analysis was performed at an embryonic stage where most cranial neural crest have emigrated from the neural tube, Wnt1-Cre mediated ?
Wnt1 Binding (embryonic stage) of in cranial neural crest
3) Confidence 0.32 Published 2010 Journal BMC Dev Biol Section Body Doc Link PMC2874773 Disease Relevance 0.52 Pain Relevance 0
In addition, the branchial arches of Spry1;R26R:Wnt1-Cre embryos were smaller than that of the R26R;Wnt1-Cre control embryos, however ?
Wnt1 Binding (embryos) of in embryos
4) Confidence 0.32 Published 2010 Journal BMC Dev Biol Section Body Doc Link PMC2874773 Disease Relevance 0.21 Pain Relevance 0

General Comments

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