INT217648

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.89
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Hmgcr) aging (Hmgcr) endoplasmic reticulum (Hmgcr)
embryo development (Hmgcr)
fa (Mus musculus)
Hmgcr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Bioavailability 2 56.12 Quite High
Nicotine 2 18.92 Low Low
Inflammation 13 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
Bile 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 7 98.60 Very High Very High Very High
Increased Venous Pressure Under Development 4 87.56 High High
Stress 17 80.00 Quite High
Hypotension 3 74.60 Quite High
Depression 1 69.92 Quite High
Hypertension 4 67.88 Quite High
Pressure And Volume Under Development 1 66.68 Quite High
Stroke 1 65.44 Quite High
Coronary Heart Disease 3 52.88 Quite High
Disorder Of Lipid Metabolism 1 43.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Reports have shown that FA exerts hypolipidemic activity by decreasing the HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis and acyl-CoA: cholesterol transferase (ACAT), the cholesterol-esterifying enzyme in tissues, and by increasing the acidic sterol excretion [71].
FA Binding (decreasing) of HMG-CoA reductase
1) Confidence 0.00 Published 2007 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2127228 Disease Relevance 0.89 Pain Relevance 0.03

General Comments

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