INT217660

Context Info Confidence 0.14 First Reported 2006 Last Reported 2009 Negated 1 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.49 Pain Relevance 0

extracellular space (MSTN) growth (MSTN) extracellular region (MSTN) cytoplasm (MSTN)

Anatomy Link Frequency muscle 1 body 1 MSTN (Homo sapiens)

Pain Link Frequency Relevance Heat imagery 22 5.00 Inflammation 12 5.00 positron emission tomography 6 5.00 qutenza 6 5.00 antidepressant 4 5.00 Spinal cord 3 5.00 cytokine 3 5.00 depression 3 5.00 Central nervous system 2 5.00 Serotonin 2 5.00

Disease Link Frequency Relevance Heat Frailty 35 99.44 Appetite Loss 5 86.24 Body Weight 4 71.52 Acquired Immune Deficiency Syndrome Or Hiv Infection 2 65.44 Aging 13 5.00 INFLAMMATION 12 5.00 Injury 8 5.00 Obesity 7 5.00 Mobility Limitation 5 5.00 Insulin Resistance 5 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Thus, while myostatin is an important target in combating muscle wasting, the role of age-related changes in myostatin expression is still a controversial subject.

Regulation (target) of myostatin in muscle associated with frailty

1) Confidence 0.14 Published 2009 Journal Osteoporos Int Section Body Doc Link PMC2832869 Disease Relevance 0.26 Pain Relevance 0

However, Willoughby [44] reported that 1,200 milligrams/day of Cystoseira canariensis supplementation during 12 weeks of resistance training had no effect on serum myostatin levels, not did it have any effect on muscle mass, muscle strength, or body fat.

Neg (no) Regulation (effect) of myostatin in body

2) Confidence 0.05 Published 2006 Journal J Int Soc Sports Nutr Section Body Doc Link PMC2129138 Disease Relevance 0.22 Pain Relevance 0

General Comments

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