INT217686

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Context Info
Confidence 0.26
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.97
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (SHBG)
SHBG (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 11 93.44 High High
drug abuse 1 63.76 Quite High
Arthritis 1 37.48 Quite Low
Neuropeptide 13 5.00 Very Low Very Low Very Low
behavioral therapy 8 5.00 Very Low Very Low Very Low
Serotonin 6 5.00 Very Low Very Low Very Low
Cholecystokinin 5 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Bile 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anovulation 2 100.00 Very High Very High Very High
Obesity 270 97.56 Very High Very High Very High
Reprotox - General 3 2 94.80 High High
Knee Osteoarthritis 4 93.44 High High
Overweight 38 91.56 High High
Weight Gain 8 87.84 High High
Osteoarthritis 7 73.96 Quite High
Hypertension 15 68.28 Quite High
Drug Dependence 1 63.76 Quite High
Crystal Associated Disease 1 40.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Obesity can affect fertility due to hormonal alterations that include: increased levels of gonadatropins and androgens which may cause anovulation, reduction in sex-hormone-binding globulin (SHBG), and increasing biologically active free androgens which are associated with anovulation.
Positive_regulation (cause) of Negative_regulation (reduction) of SHBG associated with obesity and anovulation
1) Confidence 0.26 Published 2005 Journal J Int Soc Sports Nutr Section Body Doc Link PMC2129146 Disease Relevance 1.97 Pain Relevance 0.33

General Comments

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