INT217725

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Context Info
Confidence 0.45
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.21
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (EPHB1) signal transduction (EPHB1) plasma membrane (EPHB1)
cytoplasm (EPHB1)
Anatomy Link Frequency
stem cells 1
EPHB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Action potential 3 57.60 Quite High
Potency 4 5.00 Very Low Very Low Very Low
tetrodotoxin 3 5.00 Very Low Very Low Very Low
opiate 3 5.00 Very Low Very Low Very Low
Sciatic nerve 3 5.00 Very Low Very Low Very Low
Opioid 3 5.00 Very Low Very Low Very Low
Migraine 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertrophy 5 78.20 Quite High
Obesity 6 75.00 Quite High
Disease 14 5.00 Very Low Very Low Very Low
Apoptosis 7 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Adverse Drug Reaction 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
Brain Injury 3 5.00 Very Low Very Low Very Low
Unconsciousness 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Support of PAED-Net/KKS is double as high as support by CROs which is represented by the total number of studies (35 versus 3).
Localization (Support) of PAED-Net
1) Confidence 0.45 Published 2008 Journal GMS German Medical Science Section Body Doc Link PMC2703255 Disease Relevance 0 Pain Relevance 0
Implementation of the KKS (Coordinating Centres for Clinical Trials) and PAED-Net, a “Pediatric Network on Medication Development and Testing in Children and Adolescents at KKS” is an initiative of the Federal Ministry for Education and Research in Germany (BMBF).
Localization (Implementation) of PAED-Net
2) Confidence 0.39 Published 2008 Journal GMS German Medical Science Section Body Doc Link PMC2703255 Disease Relevance 0 Pain Relevance 0
Global gene expression analysis results showed that Oct4 regulated target genes which could be characterized as differentially regulated genes such as pluripotency markers NANOG, SOX2, and KLF4 and markers of undifferentiated stem cells FOXD1, CDC2, and EPHB1.
Localization (undifferentiated) of EPHB1 in stem cells
3) Confidence 0.24 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2747014 Disease Relevance 0.13 Pain Relevance 0.03
In fact, while there was a net uptake of amino acids with the EARLY condition, there was a net release of amino acids in the LATE condition.
Localization (release) of net
4) Confidence 0.03 Published 2006 Journal J Int Soc Sports Nutr Section Body Doc Link PMC2129150 Disease Relevance 0.08 Pain Relevance 0

General Comments

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