INT217733

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Context Info
Confidence 0.51
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 1.97
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (AMH) extracellular space (AMH) aging (AMH)
extracellular region (AMH) cell-cell signaling (AMH) cytoplasm (AMH)
Anatomy Link Frequency
follicles 1
AMH (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 89 99.22 Very High Very High Very High
Perioperative pain 1 84.88 Quite High
cINOD 78 56.16 Quite High
COX-2 inhibitor 46 50.00 Quite Low
dexamethasone 2 46.56 Quite Low
cva 4 14.00 Low Low
Inflammation 12 5.00 Very Low Very Low Very Low
rheumatoid arthritis 8 5.00 Very Low Very Low Very Low
Osteoarthritis 8 5.00 Very Low Very Low Very Low
Arthritis 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stroke 6 99.80 Very High Very High Very High
Polycystic Ovary Syndrome 116 94.88 High High
Insulin Resistance 14 90.64 High High
Myocardial Infarction 65 89.88 High High
Sudden Death 1 85.48 High High
Post Operative Pain 1 84.88 Quite High
Respiratory Disease 1 83.52 Quite High
Adenoma 3 73.88 Quite High
Adenomatous Polyps 2 69.88 Quite High
Pulmonary Disease 1 65.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The reason for the reduction in AMH concentrations after metformin remains still controversial.
Negative_regulation (reduction) of AMH
1) Confidence 0.51 Published 2010 Journal J Ovarian Res Section Body Doc Link PMC2912910 Disease Relevance 0.52 Pain Relevance 0
Moreover, Piltonen et al. [9], in a prospective study, showed that the AMH levels, the number of antral follicles and the ovarian volume were reduced after metformin administration.
Negative_regulation (reduced) of AMH in follicles
2) Confidence 0.37 Published 2010 Journal J Ovarian Res Section Body Doc Link PMC2912910 Disease Relevance 0.50 Pain Relevance 0
These data are consistent with the notion that aspirin is less efficacious in women (for the reduction of MIs) and raise the possibility that women are more susceptible to aspirin resistance.


Negative_regulation (reduction) of MIs associated with aspirin
3) Confidence 0.34 Published 2007 Journal BMC Med Section Body Doc Link PMC2131749 Disease Relevance 0.31 Pain Relevance 0.24
Haptic feedback in VR (MIS) training
Negative_regulation (feedback) of MIS
4) Confidence 0.18 Published 2009 Journal Surg Endosc Section Body Doc Link PMC2686803 Disease Relevance 0 Pain Relevance 0
A divergence in risk for serious cardiovascular events was observed after 18 months of therapy (Fig. 1), primarily reflecting a greater number of MIs and strokes in the rofecoxib group.
Negative_regulation (number) of MIs associated with stroke
5) Confidence 0.07 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833977 Disease Relevance 0.64 Pain Relevance 0.14

General Comments

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