INT217915

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Context Info
Confidence 0.28
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Cry1, Per2) protein binding transcription factor activity (Cry1, Per2) cytoplasm (Cry1, Per2)
signal transduction (Per2) mitochondrion (Cry1) signal transducer activity (Per2)
Anatomy Link Frequency
nucleus 1
Cry1 (Mus musculus)
Per2 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sleep Disorders 8 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Duodenal Ulcer 1 5.00 Very Low Very Low Very Low
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Cardiovascular Disease 1 5.00 Very Low Very Low Very Low
Affective Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Changes that prolong the half-life for CRY1 in the nucleus (faster dissociation of PER2-bound CRY1 species and slower CRY1 degradation) result in a longer period, a fact that was recently confirmed in experimental studies [31].
CRY1 Binding (dissociation) of PER2 in nucleus
1) Confidence 0.28 Published 2007 Journal PLoS Computational Biology Section Body Doc Link PMC2134962 Disease Relevance 0 Pain Relevance 0

General Comments

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