INT217952

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.85
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (MYH7) ATPase activity (MYH7) nucleus (MYH7)
cytoplasm (MYH7)
Anatomy Link Frequency
cranial 1
heart 1
MYH7 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 1 91.64 High High
Catecholamine 1 88.80 High High
Inflammation 1 44.04 Quite Low
fibrosis 1 13.44 Low Low
fluoxetine 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 95.00 High High
Infection 2 93.56 High High
Malaria 2 89.12 High High
Hypothyroidism 22 86.80 High High
Paroxysmal Dyspnea 1 83.92 Quite High
Heart Rate Under Development 9 81.92 Quite High
Pressure And Volume Under Development 4 80.28 Quite High
Pressure Volume 2 Under Development 1 77.84 Quite High
Intellectual Impairment 1 75.08 Quite High
Myocardial Infarction 3 70.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The human-specific loss of a myosin heavy chain isoform expressed in the masticatory muscles has been linked to the weakening of human jaw muscles, possibly allowing the increase of cranial capacity in humans, although this is still quite speculative [3].
Negative_regulation (loss) of chain isoform in cranial
1) Confidence 0.01 Published 2007 Journal PLoS Computational Biology Section Body Doc Link PMC2134963 Disease Relevance 0.41 Pain Relevance 0.05
Normal heart contractility is also related to proper tri-iodothyronine-stimulated transcription of the myosin heavy-chain alpha gene and inhibition of the heavy-chain beta gene.
Negative_regulation (inhibition) of heavy-chain beta gene in heart
2) Confidence 0.01 Published 2008 Journal Cases J Section Body Doc Link PMC2584645 Disease Relevance 1.44 Pain Relevance 0.04

General Comments

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