INT217993

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Context Info
Confidence 0.41
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ube3a) nucleus (Ube3a) ligase activity (Ube3a)
Ube3a (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 2 88.36 High High
cytokine 17 86.44 High High
Inflammatory response 6 83.68 Quite High
Inflammation 32 68.68 Quite High
tolerance 10 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Nicotine 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 4 100.00 Very High Very High Very High
Asthma 33 90.08 High High
INFLAMMATION 35 83.28 Quite High
Nicotine Addiction 46 61.60 Quite High
Disease 8 5.00 Very Low Very Low Very Low
Rhinitis 5 5.00 Very Low Very Low Very Low
Adhesions 4 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Pneumonia 4 5.00 Very Low Very Low Very Low
Diabetes Mellitus 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Among the up-regulated genes were 6 involved in positive regulation of proliferation/differentiation/growth (Kitlg, Runxlt1, Gnaz, Pik3ca, Ptprb, Tmrsf3), 7 associated with increased ubiquitination/apoptosis (Ube3a, Hip2, Casp8ap2, Gmfb, Erg, Pja2, Usp53), and 4 involved in suppression of immune responses (Hgf, Ppapdc2, Rnd3, Dpp4).
Positive_regulation (increased) of Ube3a associated with apoptosis
1) Confidence 0.41 Published 2007 Journal Environ Health Perspect Section Body Doc Link PMC2137099 Disease Relevance 0.62 Pain Relevance 0.16

General Comments

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