INT218010

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CYP27B1) small molecule metabolic process (CYP27B1) cytoplasm (CYP27B1)
EE (Homo sapiens)
CYP27B1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 1 75.84 Quite High
Potency 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 2 38.08 Quite Low
Body Weight 3 5.00 Very Low Very Low Very Low
Lymphopenia 1 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Disease Susceptibility 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Feminization 1 5.00 Very Low Very Low Very Low
Nephrotoxicity 1 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Importantly, the observed antagonism of effluent-induced CYP1A by the added EE2 may result in a compromised detoxification capacity of fish exposed to potent estrogenic effluents.
EE2 Positive_regulation (induced) of CYP1A
1) Confidence 0.05 Published 2007 Journal Environ Health Perspect Section Body Doc Link PMC2137123 Disease Relevance 0 Pain Relevance 0.04

General Comments

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