INT218247

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Context Info
Confidence 0.65
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.37
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Cardf1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
amygdala 147 90.32 High High
Central nervous system 4 77.72 Quite High
Bioavailability 4 37.84 Quite Low
opiate 2 12.60 Low Low
long-term potentiation 13 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
Glutamate 5 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 10 97.92 Very High Very High Very High
Anxiety Disorder 76 97.60 Very High Very High Very High
Death 4 82.56 Quite High
Drug Induced Neurotoxicity 16 81.68 Quite High
Coma 4 81.16 Quite High
Blindness 2 80.92 Quite High
Ataxia 6 80.48 Quite High
Sialorrhea 2 80.16 Quite High
Neurologic Manifestations 4 77.80 Quite High
Adverse Drug Reaction 4 71.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The findings of our Western blot analyses are presented in Figure 2 c–f.
Gene_expression (presented) of c-f
1) Confidence 0.65 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2888610 Disease Relevance 0.73 Pain Relevance 0.20
Additionally, sub-populations of CF-1 identified as expressing reduced levels of P-glycoprotein exhibit increased toxicity to substrates of this transporter.
Gene_expression (expressing) of CF-1 associated with toxicity
2) Confidence 0.04 Published 2003 Journal Filaria J Section Abstract Doc Link PMC2147658 Disease Relevance 0.73 Pain Relevance 0.04
Second, sub populations of CF-1 mice were identified as expressing reduced levels of P-glycoprotein, including a population that does not produce P-glycoprotein, identified as (-/-) [27].
Gene_expression (expressing) of CF-1
3) Confidence 0.04 Published 2003 Journal Filaria J Section Body Doc Link PMC2147658 Disease Relevance 0.91 Pain Relevance 0

General Comments

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