INT218286

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Context Info
Confidence 0.60
First Reported 2008
Last Reported 2008
Negated 1
Speculated 2
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.50
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Acvr2b) plasma membrane (Acvr2b) kinase activity (Acvr2b)
cytoplasm (Acvr2b)
Anatomy Link Frequency
muscle 4
Acvr2b (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 10 68.88 Quite High
Hypertrophy 4 65.64 Quite High
Muscular Atrophy 2 8.64 Low Low
Aging 2 5.00 Very Low Very Low Very Low
Confusion 2 5.00 Very Low Very Low Very Low
Hyperinsulinism 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because testosterone is assumed to be responsible for the greater muscle mass in men, an obvious issue is whether it regulates expression of GRB10 or ACVR2B genes.
Spec (whether) Regulation (regulates) of Gene_expression (expression) of ACVR2B in muscle
1) Confidence 0.60 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2148100 Disease Relevance 0.24 Pain Relevance 0
It is not known whether the polymorphisms in the ACVR2B genes in the different haplotypes affect ACVR2B expression in muscle.
Neg (not) Spec (whether) Regulation (affect) of Gene_expression (expression) of ACVR2B in muscle
2) Confidence 0.60 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2148100 Disease Relevance 0.26 Pain Relevance 0

General Comments

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