INT21842

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Context Info
Confidence 0.19
First Reported 1990
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mme) plasma membrane (Mme)
Anatomy Link Frequency
PAG 2
Mme (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 1 99.72 Very High Very High Very High
amygdala 5 98.96 Very High Very High Very High
medulla 10 98.82 Very High Very High Very High
antagonist 1 84.12 Quite High
Opioid 1 83.68 Quite High
narcan 1 79.24 Quite High
Antinociceptive 2 77.76 Quite High
tail-flick 5 64.96 Quite High
Analgesic 1 25.00 Low Low
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 8 98.74 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data suggest that in the presence of a strong thermal stimulus, the behavioral response is subject to a tonically active or stimulus-evoked modulation by the local release in the PAG, VM and AM of an agent, presumably an enkephalin peptide, the degradation of which is altered by enkephalinase inhibition.
Regulation (altered) of Protein_catabolism (degradation) of enkephalinase in PAG associated with medulla, urological neuroanatomy, enkephalin and amygdala
1) Confidence 0.19 Published 1990 Journal Brain Res. Section Abstract Doc Link 2207626 Disease Relevance 0.58 Pain Relevance 0.97

General Comments

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