INT218481

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.23
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (C3) extracellular space (C3) extracellular region (C3)
Anatomy Link Frequency
cleavage 2
C3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 10 60.64 Quite High
Inflammatory response 3 45.68 Quite Low
Pain 2 43.80 Quite Low
rheumatoid arthritis 6 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Flavivirus Infection 80 99.78 Very High Very High Very High
Disease 32 97.60 Very High Very High Very High
Dengue 104 92.72 High High
Death 2 68.36 Quite High
INFLAMMATION 13 60.64 Quite High
Pruritus 1 44.24 Quite Low
Pain 2 43.80 Quite Low
Increased Venous Pressure Under Development 2 39.36 Quite Low
Tick Paralysis 1 5.88 Low Low
Infection 39 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Patients with DHF had lower levels of complement factor 3 (C3; p?
Positive_regulation (levels) of C3 Binding (complement factor 3) of associated with flavivirus infection
1) Confidence 0.35 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2728508 Disease Relevance 1.10 Pain Relevance 0
Factor B interacts with C3b, leading to its cleavage by factor D and the formation of the C3 convertase (C3bBb).
Positive_regulation (leading) of C3 Binding (formation) of in cleavage
2) Confidence 0.11 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2151134 Disease Relevance 0.13 Pain Relevance 0.03

General Comments

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