INT218503

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.29
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cfb, C3) extracellular region (Cfb, C3) cell proliferation (Cfb)
signal transduction (C3) peptidase activity (Cfb)
Cfb (Mus musculus)
C3 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 2 69.92 Quite High
Inflammation 20 51.76 Quite High
rheumatoid arthritis 12 49.36 Quite Low
ischemia 6 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
psoriasis 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
American Trypanosomiasis 2 69.44 Quite High
Herpes Simplex Virus 2 64.04 Quite High
Pox Virus Infection 2 57.00 Quite High
INFLAMMATION 24 51.76 Quite High
Disease 30 50.72 Quite High
Rheumatoid Arthritis 12 49.36 Quite Low
Renal Disease 4 47.60 Quite Low
Systemic Lupus Erythematosus 12 45.76 Quite Low
Paroxysmal Nocturnal Hemoglobinuria 2 43.12 Quite Low
Infection 2 42.56 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This is a stable convertase that continuously cleaves component C3 and C5, leading to depletion of serum complement components [61].
convertase Positive_regulation (cleaves) of C3
1) Confidence 0.01 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2151134 Disease Relevance 0.29 Pain Relevance 0.06
Furthermore, properdin strictly acts at membrane level, mostly by stabilizing preformed C3 convertases complexes.
properdin Positive_regulation (stabilizing) of C3
2) Confidence 0.01 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2151134 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

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