INT218508

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (C3, Cfb) extracellular region (C3, Cfb) cell proliferation (Cfb)
peptidase activity (Cfb) signal transduction (C3)
C3 (Homo sapiens)
Cfb (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 10 5.00 Very Low Very Low Very Low
rheumatoid arthritis 6 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 2 48.56 Quite Low
Salivary Gland Disease 22 5.00 Very Low Very Low Very Low
Hemolysis 19 5.00 Very Low Very Low Very Low
Disease 15 5.00 Very Low Very Low Very Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 6 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 6 5.00 Very Low Very Low Very Low
Bites And Stings 3 5.00 Very Low Very Low Very Low
Immunization 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our study of this action mechanism showed that IxAC molecules bind specifically to properdin, preventing its association with C3 and thereby reducing formation of C3 convertase complex to levels observed in the absence of properdin.
Negative_regulation (preventing) of C3 Binding (association) of properdin
1) Confidence 0.01 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2151134 Disease Relevance 0 Pain Relevance 0

General Comments

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