INT218605
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
We found that while low doses were able to block EEG signs of slow wave sleep, high doses also produced seizures [21], suggesting that an increase in neuronal excitability in the cerebral cortex, due to a block of the Kv1.2-mediated current, is sufficient to trigger seizure activity. | |||||||||||||||
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Demyelination in vehicle-treated EAE was associated with increased expression of Kv1.2 and a lengthening of Kv1.2 immunostaining across the entire axon length. | |||||||||||||||
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General Comments
This test has worked.