INT218670

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Smad2) DNA binding (Smad2) protein complex (Smad2)
transcription factor binding (Smad2) cytoplasm (Smad2) signal transducer activity (Olr811)
Olr811 (Rattus norvegicus)
Smad2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 10 29.72 Quite Low
fibrosis 5 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 2 93.00 High High
Apoptosis 9 66.72 Quite High
Hepatitis C Virus Infection 10 52.16 Quite High
Cirrhosis 36 43.36 Quite Low
Fibrosis 3 5.00 Very Low Very Low Very Low
Hepatitis 2 5.00 Very Low Very Low Very Low
Disease Progression 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
signal cascades through Smad2 and Smad3 strongly regulate the expression of the type I collagen gene (27), we evaluated the effects of NIM811 on the phosphorylation of Smad2 and Smad3.
NIM811 Regulation (effects) of Phosphorylation (phosphorylation) of Smad2
1) Confidence 0.00 Published 2007 Journal Liver International Section Body Doc Link PMC2156109 Disease Relevance 0.33 Pain Relevance 0

General Comments

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