INT21868

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.42
First Reported 1990
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.40
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (GTF2A1L) DNA binding (GTF2A1L)
Anatomy Link Frequency
blood 1
platelet 1
GTF2A1L (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 4 99.40 Very High Very High Very High
Calcium channel 15 89.16 High High
Angina 4 79.52 Quite High
aspirin 1 69.72 Quite High
rapifen 5 50.00 Quite Low
potassium channel 1 26.64 Quite Low
antiarrhythmic agent 3 5.00 Very Low Very Low Very Low
beta blocker 3 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thrombosis 2 88.96 High High
Myocardial Infarction 6 81.04 Quite High
Cv General 3 Under Development 4 79.52 Quite High
Hypertension 5 5.00 Very Low Very Low Very Low
Heart Rate Under Development 5 5.00 Very Low Very Low Very Low
Arrhythmias 2 Under Development 3 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 3 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Natriuresis 1 5.00 Very Low Very Low Very Low
Coronary Vasospasm 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A post hoc simulation showed that the Cp Alfref decreased the predicted Cp Alf compared with mean arterial blood pressure alone.
Negative_regulation (decreased) of Alf in blood
1) Confidence 0.42 Published 2006 Journal Anesthesiology Section Body Doc Link 16931977 Disease Relevance 0 Pain Relevance 0
These have spurred the development of novel drugs, such as platelet fibrinogen receptor antagonists, plasminogen activators, and inhibitors of factor IIa (thrombin) and XIIIa.
Negative_regulation (inhibitors) of factor IIa in platelet associated with antagonist
2) Confidence 0.12 Published 1990 Journal FASEB J. Section Abstract Doc Link 2210155 Disease Relevance 0.40 Pain Relevance 0.16
The first cluster, with negative values of factor 1 factor 2, contains nifedipine, nimodipine, nisoldipine, nitrendipine as 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate derivatives with a nitro- group attached to position 2 or 3 of phenyl moiety, and belongs pharmacologically to the dihydropyridine class selective calcium channel blockers with lack of antiarrhythmic activity and additionally characterized by antihypertension activity (Table 1).
Negative_regulation (values) of factor 1 factor 2 associated with calcium channel
3) Confidence 0.01 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2920560 Disease Relevance 0 Pain Relevance 0.10

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox