INT218703

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mapk8) signal transduction (Mapk8) mitochondrion (Mapk8)
plasma membrane (EPHB2) nucleus (Mapk8) kinase activity (Mapk8)
Mapk8 (Rattus norvegicus)
EPHB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 10 53.64 Quite High
fibrosis 5 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 9 90.64 High High
Cancer 2 71.20 Quite High
Cirrhosis 36 5.00 Very Low Very Low Very Low
Hepatitis C Virus Infection 10 5.00 Very Low Very Low Very Low
Fibrosis 3 5.00 Very Low Very Low Very Low
Hepatitis 2 5.00 Very Low Very Low Very Low
Disease Progression 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because cell growth and the expression of genes involved in the process of cell growth are widely regulated through MAPK signal cascades, we assessed the effects of NIM811 on MAPK activity, including ERK1/2, JNK and p38.
JNK Regulation (effects) of ERK1
1) Confidence 0.04 Published 2007 Journal Liver International Section Body Doc Link PMC2156109 Disease Relevance 0.33 Pain Relevance 0.05

General Comments

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