INT218728

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Context Info
Confidence 0.22
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.40
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Hdc) lyase activity (Hdc) cellular amino acid metabolic process (Hdc)
Hdc (Mus musculus)
Pain Link Frequency Relevance Heat
Neurotransmitter 2 72.20 Quite High
Pain 2 40.72 Quite Low
Eae 4 40.32 Quite Low
Thalamus 2 31.72 Quite Low
Spinal cord 2 22.92 Low Low
cerebral cortex 6 5.00 Very Low Very Low Very Low
monoamine 4 5.00 Very Low Very Low Very Low
midbrain 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Suicidal Behaviour 6 99.98 Very High Very High Very High
Targeted Disruption 6 98.68 Very High Very High Very High
Pain 2 40.72 Quite Low
Cognitive Disorder 4 37.36 Quite Low
Anorexia 6 22.72 Low Low
Appetite Loss 4 5.00 Very Low Very Low Very Low
Decapitation 2 5.00 Very Low Very Low Very Low
Starvation 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-fluoromethylhistidine (FMH), a suicide inhibitor of histamine synthesizing histidine decarboxylase (HDC) enzyme as well as in mice with targeted disruption of histamine H1 receptors (H1KO mice) (Yoshimatsu et al. 1998; Masaki et al. 2001).
Negative_regulation (inhibitor) of Gene_expression (synthesizing) of HDC associated with targeted disruption and suicidal behaviour
1) Confidence 0.22 Published 2007 Journal Journal of Neurochemistry Section Body Doc Link PMC2156111 Disease Relevance 0.20 Pain Relevance 0.04
-fluoromethylhistidine (FMH), a suicide inhibitor of histamine synthesizing histidine decarboxylase (HDC) enzyme as well as in mice with targeted disruption of histamine H1 receptors (H1KO mice) (Yoshimatsu et al. 1998; Masaki et al. 2001).
Negative_regulation (inhibitor) of Gene_expression (synthesizing) of histidine decarboxylase associated with targeted disruption and suicidal behaviour
2) Confidence 0.19 Published 2007 Journal Journal of Neurochemistry Section Body Doc Link PMC2156111 Disease Relevance 0.20 Pain Relevance 0.04

General Comments

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