INT21873

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.50
First Reported 1988
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 2.09
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nbr1) lysosome (Nbr1) cytoplasm (Nbr1)
Anatomy Link Frequency
epithelial cells 4
Nbr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dismenorea 8 99.54 Very High Very High Very High
endometriosis 4 99.28 Very High Very High Very High
Pain 1 27.28 Quite Low
Disease Link Frequency Relevance Heat
Breast Cancer 10 100.00 Very High Very High Very High
Ovarian Cancer 1 100.00 Very High Very High Very High
Dysmenorrhea 7 99.54 Very High Very High Very High
Endometriosis (extended) 4 99.28 Very High Very High Very High
Gynecological Disease 1 95.48 Very High Very High Very High
Cancer 4 80.40 Quite High
Appendicitis 3 74.08 Quite High
Ovarian Hyperstimulation Syndrome 3 73.40 Quite High
Cyst 3 67.92 Quite High
Disease 3 45.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Seven of these patients had positive results in transvaginal ultrasonography; 61%(11/18) patients had elevated CA125 levels.
Positive_regulation (elevated) of Gene_expression (levels) of CA125
1) Confidence 0.50 Published 2009 Journal Zhejiang Da Xue Xue Bao Yi Xue Ban Section Body Doc Link 19830869 Disease Relevance 0.08 Pain Relevance 0
Human eutopic and heterotopic endometrium were cultured and epithelial cells were isolated from stromal cells by the modified method of Satyaswaroop et al. in order to investigate the cause of elevated serum CA125 levels in patients with adenomyosis.
Positive_regulation (elevated) of Gene_expression (levels) of CA125 in epithelial cells associated with dismenorea
2) Confidence 0.46 Published 1990 Journal Nippon Sanka Fujinka Gakkai Zasshi Section Abstract Doc Link 2212818 Disease Relevance 0.10 Pain Relevance 0.10
These findings suggest that the elevation of serum CA125 levels in patients with adenomyosis may be due to greatly increased production of CA125 by heterotopic epithelial cells, in addition to the production of CA125 by eutopic ones.
Positive_regulation (increased) of Gene_expression (production) of CA125 in epithelial cells associated with dismenorea
3) Confidence 0.40 Published 1990 Journal Nippon Sanka Fujinka Gakkai Zasshi Section Abstract Doc Link 2212818 Disease Relevance 0.16 Pain Relevance 0.16
[The mechanism of the increase in the serum CA125 concentration in patients with endometriosis].
Positive_regulation (increase) of Gene_expression (concentration) of CA125 associated with endometriosis
4) Confidence 0.34 Published 1988 Journal Nippon Sanka Fujinka Gakkai Zasshi Section Title Doc Link 3163715 Disease Relevance 0.91 Pain Relevance 0.25
In breast cancer there is often overexpression of the breast cancer antigen CA15-3, the carcinoembryonic antigen (CEA) and the ovarian cancer antigen CA125, which makes them potential target antigens for immunotherapy.
Positive_regulation (overexpression) of Gene_expression (overexpression) of CA125 associated with ovarian cancer and breast cancer
5) Confidence 0.07 Published 2000 Journal Cancer Biother. Radiopharm. Section Abstract Doc Link 11155821 Disease Relevance 0.84 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox