INT218733

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Context Info
Confidence 0.27
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Hdc) lyase activity (Hdc) extracellular region (Trh)
plasma membrane (Trh) nucleus (Trh) cellular amino acid metabolic process (Hdc)
Trh (Rattus norvegicus)
Hdc (Mus musculus)
Pain Link Frequency Relevance Heat
cerebral cortex 6 92.44 High High
monoamine 4 5.00 Very Low Very Low Very Low
Eae 4 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
midbrain 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Thalamus 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Starvation 2 41.28 Quite Low
Anorexia 6 34.08 Quite Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Suicidal Behaviour 6 5.00 Very Low Very Low Very Low
Cognitive Disorder 4 5.00 Very Low Very Low Very Low
Appetite Loss 4 5.00 Very Low Very Low Very Low
Decapitation 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, TRH at the dose of 1–50 nmol increased HDC expression in a dose-dependent manner (Fig. 6c).


TRH Positive_regulation (increased) of Gene_expression (expression) of HDC
1) Confidence 0.27 Published 2007 Journal Journal of Neurochemistry Section Body Doc Link PMC2156111 Disease Relevance 0 Pain Relevance 0.04
Moreover, HDC expression was increased by microinfusion of TRH at 10 and 50 nmol into the TMN but not at 1 nmol dose of TRH.
TRH Neg (not) Positive_regulation (increased) of Gene_expression (expression) of HDC
2) Confidence 0.24 Published 2007 Journal Journal of Neurochemistry Section Body Doc Link PMC2156111 Disease Relevance 0 Pain Relevance 0.05

General Comments

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