INT218783

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.55
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Faah) extracellular region (Cfp) Golgi apparatus (Faah)
endoplasmic reticulum (Faah) cytoplasm (Faah)
Anatomy Link Frequency
hippocampus 1
Faah (Mus musculus)
Cfp (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 11 99.88 Very High Very High Very High
Endocannabinoid 62 90.92 High High
antidepressant 66 89.56 High High
fluoxetine 10 68.20 Quite High
antagonist 5 57.40 Quite High
amygdala 1 39.00 Quite Low
depression 82 36.64 Quite Low
Cannabinoid 13 5.00 Very Low Very Low Very Low
monoamine 11 5.00 Very Low Very Low Very Low
agonist 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 4 96.70 Very High Very High Very High
Targeted Disruption 13 77.12 Quite High
Obesity 1 60.08 Quite High
Stress 15 50.80 Quite High
Depression 91 36.64 Quite Low
Neurodegenerative Disease 15 5.00 Very Low Very Low Very Low
Manic Depressive Disorder 10 5.00 Very Low Very Low Very Low
Suicidal Behaviour 8 5.00 Very Low Very Low Very Low
Affective Disorder 6 5.00 Very Low Very Low Very Low
Psychosis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A single administration of ECS produces a reduction in the affinity of CB1 receptors in the PFC, hippocampus, hypothalamus and amigdala, reduces anandamide levels in the PFC and hippocampus, and FAAH activity in the PFC.
FAAH Binding (activity) of PFC in hippocampus associated with shock and hippocampus
1) Confidence 0.04 Published 2007 Journal Clin Pract Epidemiol Ment Health Section Body Doc Link PMC2169225 Disease Relevance 0.55 Pain Relevance 0.45

General Comments

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