INT218818

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.23
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.78
Pain Relevance 1.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Ppp1r9a)
Ppp1r9a (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 110 98.76 Very High Very High Very High
depression 78 98.48 Very High Very High Very High
Hippocampus 24 89.44 High High
nMDA receptor 30 57.08 Quite High
Acute pain 2 41.04 Quite Low
Pyramidal cell 12 15.16 Low Low
tail-flick 8 5.00 Very Low Very Low Very Low
amygdala 6 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
cocaine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 78 98.48 Very High Very High Very High
Targeted Disruption 180 94.12 High High
Anxiety Disorder 56 73.52 Quite High
Pain 4 41.04 Quite Low
Hypesthesia 2 29.68 Quite Low
Shock 14 27.52 Quite Low
Nociception 6 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fourth, neurabin-binding PP1 may not directly modulate LTP or LTD.
neurabin Binding (binding) of associated with depression and long-term potentiation
1) Confidence 0.23 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2169299 Disease Relevance 1.14 Pain Relevance 0.62
Using virus-mediated expression of mutant neurabin, which is unable to bind PP1 or F-actin, it was found to attenuate LTD, increase LTP and decrease basal synaptic transmission in hippocampal slice culture [25], [26].
neurabin Neg (unable) Binding (bind) of associated with depression and long-term potentiation
2) Confidence 0.17 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2169299 Disease Relevance 0.63 Pain Relevance 0.44

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox