INT218847

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Context Info
Confidence 0.22
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Ppp1cc) carbohydrate metabolic process (Ppp1cc) protein complex (Ppp1cc)
cytoplasm (Ppp1cc) chromosome (Ppp1cc) nucleolus (Ppp1cc)
Anatomy Link Frequency
neurons 2
Ppp1cc (Mus musculus)
Ltp (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 55 100.00 Very High Very High Very High
depression 39 99.80 Very High Very High Very High
Hippocampus 12 66.64 Quite High
Glutamate 1 15.08 Low Low
nMDA receptor 15 5.00 Very Low Very Low Very Low
Pyramidal cell 6 5.00 Very Low Very Low Very Low
tail-flick 4 5.00 Very Low Very Low Very Low
amygdala 3 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
cocaine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 39 99.80 Very High Very High Very High
Targeted Disruption 90 90.08 High High
Anxiety Disorder 28 50.00 Quite Low
Shock 7 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Hypesthesia 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PP1 is known to play a major role in the control of LTP and LTD in hippocampal CA1 neurons [36].
PP1 Positive_regulation (role) of Regulation (control) of LTP in neurons associated with depression and long-term potentiation
1) Confidence 0.22 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2169299 Disease Relevance 0.46 Pain Relevance 0.29

General Comments

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