INT218903

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Context Info
Confidence 0.42
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 10
Total Number 12
Disease Relevance 5.19
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Bcl2l11) mitochondrion (Bcl2l11) cytoplasm (Bcl2l11)
Bcl2l11 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 237 100.00 Very High Very High Very High
dorsal root ganglion 60 62.76 Quite High
qutenza 51 5.00 Very Low Very Low Very Low
dexamethasone 43 5.00 Very Low Very Low Very Low
imagery 18 5.00 Very Low Very Low Very Low
trigeminal ganglion 12 5.00 Very Low Very Low Very Low
adenocard 9 5.00 Very Low Very Low Very Low
anesthesia 8 5.00 Very Low Very Low Very Low
withdrawal 7 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 101 100.00 Very High Very High Very High
Apoptosis 518 97.48 Very High Very High Very High
Poisoning 72 67.28 Quite High
Ganglion Cysts 75 62.76 Quite High
Parkinson's Disease 16 51.68 Quite High
Nociception 51 50.00 Quite Low
Stress 145 46.08 Quite Low
Aseptic Necrosis Of Bone 1 45.16 Quite Low
Osteoporosis 27 30.16 Quite Low
Lifespan 1 14.32 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Arsenic significantly increased cellular BimEL protein expression, whereas treatment with taurine could reduce this alteration (Fig. 5E).


Gene_expression (expression) of BimEL protein
1) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935368 Disease Relevance 0.46 Pain Relevance 0
Bim exists at the protein level as three isoforms, including Bim extra long (BimEL), Bim long (BimL), and Bim short (BimS).
Gene_expression (extra) of BimS
2) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935368 Disease Relevance 0.55 Pain Relevance 0
Bim exists at the protein level as three isoforms, including Bim extra long (BimEL), Bim long (BimL), and Bim short (BimS).
Gene_expression (long) of Bim
3) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935368 Disease Relevance 0.54 Pain Relevance 0
Bim exists at the protein level as three isoforms, including Bim extra long (BimEL), Bim long (BimL), and Bim short (BimS).
Gene_expression (long) of Bim
4) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935368 Disease Relevance 0.54 Pain Relevance 0
Bim exists at the protein level as three isoforms, including Bim extra long (BimEL), Bim long (BimL), and Bim short (BimS).
Gene_expression (extra) of BimEL
5) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935368 Disease Relevance 0.54 Pain Relevance 0
Bim exists at the protein level as three isoforms, including Bim extra long (BimEL), Bim long (BimL), and Bim short (BimS).
Gene_expression (extra) of BimL
6) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935368 Disease Relevance 0.54 Pain Relevance 0
Bim exists at the protein level as three isoforms, including Bim extra long (BimEL), Bim long (BimL), and Bim short (BimS).
Gene_expression (extra) of Bim
7) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935368 Disease Relevance 0.54 Pain Relevance 0
Bim exists at the protein level as three isoforms, including Bim extra long (BimEL), Bim long (BimL), and Bim short (BimS).
Gene_expression (long) of BimS
8) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935368 Disease Relevance 0.55 Pain Relevance 0
Menthol-induced responses were not significantly altered when cells were only treated with BIM (1 ?
Gene_expression (treated) of BIM
9) Confidence 0.09 Published 2010 Journal Mol Pain Section Body Doc Link PMC2936373 Disease Relevance 0.05 Pain Relevance 0.14
F/Fo: 0.88 ± 0.22, 89.79 ± 16.3% of control, n = 6 cells, 2 dishes) or the specific PKC inhibitor BIM (1 ?
Gene_expression (specific) of BIM associated with kinase c
10) Confidence 0.09 Published 2010 Journal Mol Pain Section Body Doc Link PMC2936373 Disease Relevance 0.06 Pain Relevance 0.16
F/Fo: 0.88 ± 0.22, 89.79 ± 16.3% of control, n = 6 cells, 2 dishes) or the specific PKC inhibitor BIM (1 ?
Gene_expression (0.22) of BIM associated with kinase c
11) Confidence 0.09 Published 2010 Journal Mol Pain Section Body Doc Link PMC2936373 Disease Relevance 0.06 Pain Relevance 0.16
Activation of caspase 9 is prevented by a balance being maintained between prosurvival Bcl-2 and Bcl-XL and pro-death Bad, Bid, Bim, Bax, Bak and others.
Gene_expression (prosurvival) of Bim associated with death
12) Confidence 0.07 Published 2007 Journal The Journal of Endocrinology Section Body Doc Link PMC2173947 Disease Relevance 0.76 Pain Relevance 0

General Comments

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