INT218904

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Context Info
Confidence 0.42
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.12
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Birc3) protein complex (Birc3) cytoplasm (Birc3)
Birc3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 6 99.44 Very High Very High Very High
dexamethasone 43 89.72 High High
anesthesia 3 69.16 Quite High
metalloproteinase 16 50.00 Quite Low
Hippocampus 5 21.40 Low Low
withdrawal 7 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 118 100.00 Very High Very High Very High
Cv Unclassified Under Development 4 99.44 Very High Very High Very High
Death 27 97.88 Very High Very High Very High
Hypoxia 39 91.36 High High
Hyperoxia 15 80.96 Quite High
Osteoporosis 27 73.44 Quite High
Sleep Disorders 1 64.92 Quite High
Injury 8 5.00 Very Low Very Low Very Low
Rhinitis 3 5.00 Very Low Very Low Very Low
Asphyxia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Another explanation could be that global ischemia induces endogenous caspase inhibitors, such as IAP proteins (inhibitor of apoptosis), that can bind and inhibit activated caspases [51].
Negative_regulation (inhibitors) of IAP associated with ischemia and apoptosis
1) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3000320 Disease Relevance 1.00 Pain Relevance 0.12
We assessed the transcriptional profiles of seven anti-apoptotic proteins (Bcl-2, Bcl-XL, inhibitors of apoptosis protein-1 (IAP-1), IAP-2, X-linked IAP (XIAP), Fas-associated death-domain-like IL-1?
Negative_regulation (inhibitors) of apoptosis protein-1 associated with apoptosis and death
2) Confidence 0.04 Published 2007 Journal The Journal of Endocrinology Section Abstract Doc Link PMC2173947 Disease Relevance 1.12 Pain Relevance 0.16

General Comments

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