INT218908

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.11
First Reported 2007
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 1.45
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Akp3)
Anatomy Link Frequency
osteoblasts 1
Akp3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dexamethasone 172 99.64 Very High Very High Very High
withdrawal 28 21.60 Low Low
cINOD 8 12.68 Low Low
corticosteroid 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 440 99.30 Very High Very High Very High
Death 52 88.00 High High
Repression 4 32.40 Quite Low
Osteoporosis 108 18.56 Low Low
INFLAMMATION 4 12.16 Low Low
Breast Cancer 4 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low
Obesity 4 5.00 Very Low Very Low Very Low
Aging 4 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Instead, Dex up-regulated the expression of Bcl-XL, IAP-2 and XIAP, while the transcript levels of the anti-apoptotic proteins Bcl-2, IAP-1, FLIPLong and FLIPShort were unaltered by Dex treatment.
Gene_expression (expression) of IAP-2 associated with apoptosis and dexamethasone
1) Confidence 0.11 Published 2007 Journal The Journal of Endocrinology Section Body Doc Link PMC2173947 Disease Relevance 0.55 Pain Relevance 0.27
In order to explore the possible downstream effectors of GC-induced apoptosis further, we employed rtqPCR to examine the expression of the major families of prosurvival genes (Bcl-2, Bcl-XL, IAP-1, IAP-2, XIAP, FLIPLong and FLIPShort) in osteoblasts subjected to high-dose Dex.
Spec (examine) Gene_expression (expression) of IAP-2 in osteoblasts associated with apoptosis and dexamethasone
2) Confidence 0.11 Published 2007 Journal The Journal of Endocrinology Section Body Doc Link PMC2173947 Disease Relevance 0.55 Pain Relevance 0.23
 ; mouse IAP-2 (accession no.
Gene_expression (accession) of IAP-2
3) Confidence 0.10 Published 2007 Journal The Journal of Endocrinology Section Body Doc Link PMC2173947 Disease Relevance 0.07 Pain Relevance 0
Briefly, gene transcript levels of the GC-insensitive house keeping gene, the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and the anti-apoptotic mouse genes Bcl-2, Bcl-XL, IAP-1, IAP-2, X-linked IAP (XIAP), FLIPLong and FLIPShort were quantified by rtqPCR on a LightCycler (Roche Diagnostic Systems).
Gene_expression (quantified) of IAP-2 associated with apoptosis
4) Confidence 0.10 Published 2007 Journal The Journal of Endocrinology Section Body Doc Link PMC2173947 Disease Relevance 0.29 Pain Relevance 0.03

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox