INT218915

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Context Info
Confidence 0.09
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.04
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Alpi)
Alpi (Rattus norvegicus)
Pain Link Frequency Relevance Heat
withdrawal 14 98.56 Very High Very High Very High
dexamethasone 86 97.98 Very High Very High Very High
cINOD 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 220 100.00 Very High Very High Very High
Osteoporosis 54 86.16 High High
Death 26 51.24 Quite High
Diabetes Mellitus 2 18.88 Low Low
Repression 2 5.00 Very Low Very Low Very Low
Breast Cancer 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Analogous to, although different from the observed effects of Dex exposure, mitogen withdrawal also did not decrease expression of any prosurvival genes, and instead resulted in increased transcription of the anti-apoptotic proteins Bcl-2, IAP-1, IAP-2, FLIPLong and FLIPShort.
Neg (not) Positive_regulation (resulted) of Transcription (transcription) of IAP-1 associated with apoptosis, withdrawal and dexamethasone
1) Confidence 0.09 Published 2007 Journal The Journal of Endocrinology Section Body Doc Link PMC2173947 Disease Relevance 0.52 Pain Relevance 0.31
Analogous to, although different from the observed effects of Dex exposure, mitogen withdrawal also did not decrease expression of any prosurvival genes, and instead resulted in increased transcription of the anti-apoptotic proteins Bcl-2, IAP-1, IAP-2, FLIPLong and FLIPShort.
Positive_regulation (increased) of Transcription (transcription) of IAP-1 associated with apoptosis, withdrawal and dexamethasone
2) Confidence 0.06 Published 2007 Journal The Journal of Endocrinology Section Body Doc Link PMC2173947 Disease Relevance 0.52 Pain Relevance 0.28

General Comments

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