INT218935

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.08
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Cyp3a23/3a1, Bcl2) endoplasmic reticulum (Cyp3a23/3a1, Bcl2) mitochondrion (Bcl2)
cell morphogenesis (Bcl2) intracellular (Bcl2) response to stress (Bcl2)
Cyp3a23/3a1 (Rattus norvegicus)
Bcl2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dexamethasone 86 100.00 Very High Very High Very High
withdrawal 14 69.04 Quite High
cINOD 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 220 100.00 Very High Very High Very High
Death 26 98.24 Very High Very High Very High
Osteoporosis 54 87.04 High High
Repression 2 18.04 Low Low
Breast Cancer 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Instead, Dex up-regulated the expression of Bcl-XL, IAP-2 and XIAP, while the transcript levels of the anti-apoptotic proteins Bcl-2, IAP-1, FLIPLong and FLIPShort were unaltered by Dex treatment.
Dex Regulation (unaltered) of anti-apoptotic proteins Bcl-2 associated with apoptosis and dexamethasone
1) Confidence 0.00 Published 2007 Journal The Journal of Endocrinology Section Body Doc Link PMC2173947 Disease Relevance 0.56 Pain Relevance 0.28
The transcript levels of anti-apoptotic proteins Bcl-2, IAP-1, FLIPLong and FLIPShort were not detectably altered by Dex treatment.
Dex Neg (not) Regulation (altered) of anti-apoptotic proteins Bcl-2 associated with apoptosis and dexamethasone
2) Confidence 0.00 Published 2007 Journal The Journal of Endocrinology Section Body Doc Link PMC2173947 Disease Relevance 0.52 Pain Relevance 0.46

General Comments

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