INT218972

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Context Info
Confidence 0.28
First Reported 2007
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.46
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pgr) nucleolus (Pgr) nucleus (Pgr)
enzyme binding (Pgr) cytoplasm (Pgr)
Anatomy Link Frequency
uterine 2
duct 2
Pgr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Body Weight 29 93.12 High High
Cancer 10 86.96 High High
Weight Gain 5 70.32 Quite High
Congenital Anomalies 4 10.48 Low Low
Toxicity 20 5.00 Very Low Very Low Very Low
Endometriosis (extended) 8 5.00 Very Low Very Low Very Low
Hyperplasia 7 5.00 Very Low Very Low Very Low
Pyometra 5 5.00 Very Low Very Low Very Low
Reprotox - General 1 4 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The reason the E2 high did not stimulate PR receptor as profoundly as did E2 low remains obscure, particularly in view of the profound stimulation of mammary duct tissue with luminal formation and secretory activity by the E2 high.
Neg (not) Positive_regulation (stimulate) of PR Neg (not) Binding (receptor) of in duct
1) Confidence 0.28 Published 2007 Journal Environ Health Perspect Section Body Doc Link PMC2174401 Disease Relevance 0.15 Pain Relevance 0
uterine insulin-like growth factor 1, progesterone receptor, and complement
Positive_regulation (uterine) of progesterone receptor Binding (complement) of in uterine
2) Confidence 0.06 Published 2009 Journal Journal of Toxicology Section Body Doc Link PMC2809433 Disease Relevance 0.31 Pain Relevance 0

General Comments

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