INT219149

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (FBXO8, IL10) extracellular space (IL10) extracellular region (IL10)
cell-cell signaling (IL10) response to stress (IL10) cytoplasm (FBXO8)
Anatomy Link Frequency
T cells 2
FBXO8 (Homo sapiens)
IL10 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 3 94.72 High High
cytokine 11 43.20 Quite Low
Inflammatory response 2 35.76 Quite Low
Multiple sclerosis 1 13.12 Low Low
psoriasis 7 6.96 Low Low
Inflammation 16 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
vagus nerve 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Communicable Diseases 5 71.28 Quite High
Cancer 37 70.00 Quite High
General Immunology 4 45.76 Quite Low
Autoimmune Disease 8 38.16 Quite Low
INFLAMMATION 17 35.76 Quite Low
Infection 9 28.24 Quite Low
Disease 24 14.64 Low Low
Demyelinating Disease 1 13.12 Low Low
Psoriasis 8 6.96 Low Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DC10, defined as monocyte-derived DCs generated in the presence of IL-10, promote IL-10-secreting anergic CD4+ T cells with suppressive functions (T regulatory type 1, Tr1 or IL-10-Treg).
DC10 Positive_regulation (promote) of Localization (secreting) of IL-10 in T cells
1) Confidence 0.01 Published 2007 Journal J Transl Med Section Body Doc Link PMC2176053 Disease Relevance 0.14 Pain Relevance 0.05

General Comments

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