INT219151

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.05
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (IL18, CASP1) cytosol (IL18, CASP1) intracellular (CASP1)
cell-cell signaling (IL18) extracellular space (IL18) signal transduction (CASP1)
IL18 (Homo sapiens)
CASP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 16 99.00 Very High Very High Very High
antagonist 6 90.00 High High
anakinra 1 88.40 High High
vagus nerve 2 81.12 Quite High
agonist 6 58.88 Quite High
cytokine 11 57.04 Quite High
Arthritis 2 36.56 Quite Low
tolerance 3 23.88 Low Low
psoriasis 7 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 17 99.00 Very High Very High Very High
Disease 24 98.48 Very High Very High Very High
Syndrome 1 97.60 Very High Very High Very High
Crystal Associated Disease 4 96.44 Very High Very High Very High
Shock 1 77.92 Quite High
Injury 1 76.56 Quite High
Diabetes Mellitus 1 52.52 Quite High
Autoimmune Disease 8 40.52 Quite Low
Hodgkin's Disease 1 38.44 Quite Low
Septic Shock 1 37.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
and IL-18 secretion by activating caspase-1, causes a familial auto inflammatory disease, Muckel Wells syndrome.
IL-18 Positive_regulation (activating) of caspase-1 associated with inflammation, syndrome and disease
1) Confidence 0.01 Published 2007 Journal J Transl Med Section Body Doc Link PMC2176053 Disease Relevance 1.05 Pain Relevance 0.30

General Comments

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