INT219153

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (IL6, IL23A) extracellular space (IL6) aging (IL6)
Anatomy Link Frequency
Th17 cells 1
IL6 (Homo sapiens)
IL23A (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 11 95.20 Very High Very High Very High
psoriasis 7 71.52 Quite High
Multiple sclerosis 1 68.80 Quite High
chemokine 3 67.52 Quite High
Inflammatory response 2 57.64 Quite High
Inflammation 16 25.36 Quite Low
tolerance 3 15.48 Low Low
agonist 6 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
vagus nerve 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Psoriasis 8 71.52 Quite High
Demyelinating Disease 1 68.80 Quite High
Disease 24 67.64 Quite High
Infection 9 63.44 Quite High
INFLAMMATION 17 57.24 Quite High
Autoimmune Disease 8 56.32 Quite High
General Immunology 4 45.28 Quite Low
Cancer 37 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 15 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Other studies suggest IL-6 alone potently induces Th17 cells in vitro, IL-23 showing some additive effect (Rohowsky-Kochan).
IL-6 Positive_regulation (induces) of IL-23 in Th17 cells
1) Confidence 0.02 Published 2007 Journal J Transl Med Section Body Doc Link PMC2176053 Disease Relevance 0.45 Pain Relevance 0.21

General Comments

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